Sprague Dawley

  • Nomenclature: NTac:SD
  • Model Description: Used in virtually all disciplines of biomedical research including toxicology and pharmacology. Excellent reproductive performance makes the SD rat a good model for generating timed pregnant females
  • Origin The Sprague Dawley outbred model was developed by Sprague Dawley, Inc. NIH received stock from Sprague Dawley, Inc in 1945. The rats are maintained as an outbred closed colony. Taconic received stock from the NIH Animal Genetic Resource in 1970. The rats were refreshed with NIH Genetic Resource stock in 1998
  • Color Albino
  • Coat Color Loci: Tyrc
  • Health Standard: MPF (Murine Pathogen Free)

Wistar Hannover GALAS

  • Nomenclature: HanTac:WH
  • Model Description: Frequently used as both a toxicology model and a general, all-purpose outbred model for use in biomedical research. Weighs less than SD rats but comparable to SD rats in reproductive performance Produced and maintained in adherence to international health and genetic standards agreed upon by members of the Global. Alliance for Laboratory Animal Standardization (GALAS): CLEA Japan, Inc. and Taconic Biosciences, Inc.
  • Origin The Research and Consulting Company Ltd (RCC) received 156 breeding pairs of the Wistar Hannover GALAS™ outbred model from Dr. Willy Heine of Zentralinstitut für Versuchstierzucht in Hannover Germany in 1989. The rats were derived by caesarean in 1989. Taconic received breeding stock from RCC in 1998. The rats were refreshed with cryopreserved embryos in 1998. Each member of GALAS received 50 breeding stock from RCC in 1998. The rats were derived by caesarean in 1999. Taconic replaced its previous Wistar Hannover stock with Wistar Hannover GALAS™ in June 2000.
  • Color Albino
  • Coat Color Loci: a, Tyrc, h
  • Health Standard: MPF (Murine Pathogen Free)